Drug Tetanus Antitoxin Injection for Openly Wounded

Drug Tetanus Antitoxin Injection for Openly Wounded

Product Description

TETANUS ANTISERUM  is a colorless to yellowish clear solution, free from foreign matters, prepared from immunized plasma of healthy horses through the process of ammonium sulfate fractionation and ultra-filtration after being digested with pepsin. It provides temporary passive immunity against tetanus.1500 IU – 5000 IU: For adults and children, injection should be repeated after six days when contamination still persists.For those with tetanus symptoms, Tetanus Antitoxin should be given immediately together with surgical and other clinical remedies

Product information:

[Ingredients]Equine tetanus immunoglobulin following pepsin digestion

[Pharmacological action]The product contains specific antibodies which have the power of neutralizing tetanus toxins.

[Indications]The product is used for the prophylaxis and therapy of tetanus.

[Quality Standard]CP2020

[Specifications]1500IU/0.75ml

Indication and use
1. For those openly wounded, especially those wounded deeply and contaminated seriously, and in danger of being infected with tetanus, prophylactic injection of tetanus antitoxin should be given at once. Patients who have had previous injection of tetanus toxoid should be boosted with one more injection of tetanus toxoid (but not tetanus antitoxin). To those who haven't had previous tetanus toxoid injection or without a clear history of immunization, both antitoxin and toxoid should be given for prophylaxis and permanent immunocompetence.
 
2. The right site for subcutaneous injection of the tetanujs antitoxin is around the deltoid muscle of the upper arm. If tetanus toxoid is to be given at the same time, separate sites are desirable. The right site for intramuscular injection is the centre area of the deltoid muscle or the lateral upper part of the gluteus maximum.
Intravenous route should not be used until no untoward reaction occurs after intramuscular or subcutaneuos injection. Intravenous injection should be done slowly enough: Not more than 1ml/min at the beginning and don't exceed 4ml/min afterward.
The total volume for a single dose should be not more than 40ml for adults and not more than 0.8ml of body weight for children. Tetanus antitoxin may be diluted with dextrose solution or physiological saline for intravenous drip. The drip must be stopped at once if any untoward reaction occurs.